Objectives: To investigate relationship between the lymphovascular invasion(LVI) and tumor characteristics and to evaluate effect on survival of LVI in patients who underwent radical cystectomy because of bladder cancer. Materials and Methods: Five hundred and six patients were enrolled the study between 1990 and 2013. Patients were divided into two groups in terms of lymphovascular invasion at final pathology after radical cystectomy. There were 108 patients with LVI(group1) and 244 patients without LVI(group2). Both groups were compared in terms of clinicopathologic features and survival. Results: There was no statically different for gender in both group(p=0,222).Lymh node involvement, grade, and p T stage were higher significantly in group 1(p<0,05). Positive lymph node number was 2.3±3.1 in group 1 and 0.6 ± 2.1 in group 2(p<0.001). Lymph node density was 24.3±30.1 in group 1 and 5.6±9.2 in group 2 (p<0.001).Estimated mean survival time was 27.2±3.4 months in group 1 and 80.2 ± 8.1 months in group 2 (p<0.001). Conclusions: Lymphovascular invasion is an independent prognostic factor for disease specific survival and effects survival negatively in patients who underwent radical cystectomy for bladder cancer. Patients with lymphovascular invasion should be considered for close monitoring after cystectomy.
| Published in | Clinical Medicine Research (Volume 4, Issue 2) |
| DOI | 10.11648/j.cmr.20150402.12 |
| Page(s) | 34-37 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2015. Published by Science Publishing Group |
Lymphovascular Invasion (LVI), Radical Cystectomy, Survival, Urethelial Carcinoma
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APA Style
Sacit Nuri Gorgel, Osman Kose, Ozan Horsanalı, Evren Sahin, Ugur Balci, et al. (2015). The Importance of Lymphovascular Invasion at Radical Cystectomy. Clinical Medicine Research, 4(2), 34-37. https://doi.org/10.11648/j.cmr.20150402.12
ACS Style
Sacit Nuri Gorgel; Osman Kose; Ozan Horsanalı; Evren Sahin; Ugur Balci, et al. The Importance of Lymphovascular Invasion at Radical Cystectomy. Clin. Med. Res. 2015, 4(2), 34-37. doi: 10.11648/j.cmr.20150402.12
AMA Style
Sacit Nuri Gorgel, Osman Kose, Ozan Horsanalı, Evren Sahin, Ugur Balci, et al. The Importance of Lymphovascular Invasion at Radical Cystectomy. Clin Med Res. 2015;4(2):34-37. doi: 10.11648/j.cmr.20150402.12
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Download@article{10.11648/j.cmr.20150402.12,
author = {Sacit Nuri Gorgel and Osman Kose and Ozan Horsanalı and Evren Sahin and Ugur Balci and Kutan Ozer and Cengiz Girgin},
title = {The Importance of Lymphovascular Invasion at Radical Cystectomy},
journal = {Clinical Medicine Research},
volume = {4},
number = {2},
pages = {34-37},
doi = {10.11648/j.cmr.20150402.12},
url = {https://doi.org/10.11648/j.cmr.20150402.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20150402.12},
abstract = {Objectives: To investigate relationship between the lymphovascular invasion(LVI) and tumor characteristics and to evaluate effect on survival of LVI in patients who underwent radical cystectomy because of bladder cancer. Materials and Methods: Five hundred and six patients were enrolled the study between 1990 and 2013. Patients were divided into two groups in terms of lymphovascular invasion at final pathology after radical cystectomy. There were 108 patients with LVI(group1) and 244 patients without LVI(group2). Both groups were compared in terms of clinicopathologic features and survival. Results: There was no statically different for gender in both group(p=0,222).Lymh node involvement, grade, and p T stage were higher significantly in group 1(p<0,05). Positive lymph node number was 2.3±3.1 in group 1 and 0.6 ± 2.1 in group 2(p<0.001). Lymph node density was 24.3±30.1 in group 1 and 5.6±9.2 in group 2 (p<0.001).Estimated mean survival time was 27.2±3.4 months in group 1 and 80.2 ± 8.1 months in group 2 (p<0.001). Conclusions: Lymphovascular invasion is an independent prognostic factor for disease specific survival and effects survival negatively in patients who underwent radical cystectomy for bladder cancer. Patients with lymphovascular invasion should be considered for close monitoring after cystectomy.},
year = {2015}
}
TY - JOUR T1 - The Importance of Lymphovascular Invasion at Radical Cystectomy AU - Sacit Nuri Gorgel AU - Osman Kose AU - Ozan Horsanalı AU - Evren Sahin AU - Ugur Balci AU - Kutan Ozer AU - Cengiz Girgin Y1 - 2015/02/26 PY - 2015 N1 - https://doi.org/10.11648/j.cmr.20150402.12 DO - 10.11648/j.cmr.20150402.12 T2 - Clinical Medicine Research JF - Clinical Medicine Research JO - Clinical Medicine Research SP - 34 EP - 37 PB - Science Publishing Group SN - 2326-9057 UR - https://doi.org/10.11648/j.cmr.20150402.12 AB - Objectives: To investigate relationship between the lymphovascular invasion(LVI) and tumor characteristics and to evaluate effect on survival of LVI in patients who underwent radical cystectomy because of bladder cancer. Materials and Methods: Five hundred and six patients were enrolled the study between 1990 and 2013. Patients were divided into two groups in terms of lymphovascular invasion at final pathology after radical cystectomy. There were 108 patients with LVI(group1) and 244 patients without LVI(group2). Both groups were compared in terms of clinicopathologic features and survival. Results: There was no statically different for gender in both group(p=0,222).Lymh node involvement, grade, and p T stage were higher significantly in group 1(p<0,05). Positive lymph node number was 2.3±3.1 in group 1 and 0.6 ± 2.1 in group 2(p<0.001). Lymph node density was 24.3±30.1 in group 1 and 5.6±9.2 in group 2 (p<0.001).Estimated mean survival time was 27.2±3.4 months in group 1 and 80.2 ± 8.1 months in group 2 (p<0.001). Conclusions: Lymphovascular invasion is an independent prognostic factor for disease specific survival and effects survival negatively in patients who underwent radical cystectomy for bladder cancer. Patients with lymphovascular invasion should be considered for close monitoring after cystectomy. VL - 4 IS - 2 ER -
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